RECENT publications

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Geng J, Zhang X, Prabhu S, Shahoei SH, Nelson ER, Swanson KS, Anastasio MA, Smith AM. 3Dmicroscopy and deep learning reveal the heterogeneity of crown-like structure microenvironments in intact adipose tissue. Science Advances, 7, p.eabe2480 (2021). [LINK]

Le P, Vaidya R, Smith LD, Han Z, Zahid MU, Winter J, Sarkar S, Chung HJ, Perez-Pinera P, Selvin PR, Smith AM. Optimizing quantum dot probe size for single-receptor imaging. ACS Nano, 14, 8343-8358 (2020). [LINK]

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Han Z, Sarkar, S, Smith AM. Zwitterion and oligo(ethylene glycol) synergy minimizes nonspecific binding of compact quantum dots. ACS Nano, 14, 3227-3241 (2020). [LINK]

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Sarkar S, Le P, Geng J, Liu Y, Han Z, Zahid MU, Nall D, Youn Y, Selvin PR, and Smith AM. Short-wave infrared quantum dots with compact sizes as molecular probes for fluorescence microscopy. Journal of the American Chemical Society, 142, 3449-3462 (2020). [LINK]

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Liu Y, Han Z, Sarkar S, and Smith AM. Fluorescence in situ hybridization with quantum dot labels in E. coli cells. (accepted)

Deng H, Konopka CJ, Cross T-W L, Swanson KS, Dobrucki LW, and Smith AM. Multimodal nanocarrier probes reveal superior biodistribution quantification by isotopic analysis over fluorescence. ACS Nano, 14, 1, 509-523 (2020). [LINK]

Smith LD, Liu Y, Zahid MU, Kohli M, and Smith AM. High-fidelity single molecule quantification in a flow cytometer using multiparametric optical analysis. ACS Nano, 14, 2324-2335 (2020). [LINK]

Le P, Chitoor SN, Tu C, Lim SJ, and Smith AM. Compact quantum dots for quantitative cytology. Methods in Molecular Biology: Single Cell Metabolism. 2064: 147-158 (2020). [LINK]

Canady TD, Li N, Smith LD, Kohli M, Smith AM, and Cunningham BT. Digital-resolution detection of microRNA with single-base selectivity with photonic resonance absorption microscopy. Proceedings of the National Academy of Sciences of the USA. 116: 19362-19367 (2019). [LINK]

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Ma L, Le P, Kohli M, and Smith AM. Nanomedicine in Cancer, chapter in Nanotheranostics for Cancer Applications. Springer (2019). [LINK]

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Le P, Lim SJ, Baculis BC, Chung HJ, Kilian KA, and Smith AM. Counting growth factors in single cells with near-infrared quantum dots to measure discrete stimulation distributions. Nature Communications. 10: 909 (2019) [LINK]

Smith L, Kohli M, and Smith AM. Expanding the dynamic range of fluorescence assays through single-molecule counting and intensity calibration. Journal of the American Chemical Society. 140: 13904 (2018). [LINK]

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Sheung JY, Ge P, Lim SJ, Lee SH, Smith AM, and Selvin PR. Structural contributions to hydrodynamic diameter for quantum dots optimized for live-cell single-molecule imaging. Journal of Physical Chemistry C. 122: 17406-17412 (2018). [LINK]

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Liu Y, Le P, Lim SJ, Ma L, Sarkar S, Murphy SJ, Kosari F, Vasmatzis G, Cheville JC, and Smith AM. Enhanced mRNA FISH with compact quantum dots. Nature Communications. 9: 4461 (2018). [LINK]

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Zahid MU, Ma L, Lim SJ, and Smith AM. Single quantum dot tracking reveals the impact of nanoparticle surface on intracellular state. Nature Communications. 9: 1830 (2018). [LINK]

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Ganguli A, Ornob A, Spegazzini N, Liu Y, Damhorst G, Ghonge T, Thornton B, Konopka CJ, Dobrucki W, Clare S, Smith AM, Bhargava R, Kosari F, and Bashir R. Pixelated spatial gene expression analysis for molecular histopathology. Nature Communications. 9: 202 (2018). [LINK]

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Race CM, Kwon LE, Foreman MT, Huang Q, Inan H, Kesiraju S, Le P, Lim SJ, Smith AM, Zangar RC, Demirci U, Anderson KS, and Cunningham BT. An automated microfluidic assay for photonic crystal enhanced detection and analysis of an antiviral antibody cancer biomarker in serumIEEE Sensors Journal. 18: 1464 - 1473 (2017). [LINK]

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Lim SJ, Schleife A, and Smith AM. Optical determination of crystal phase in semiconductor nanocrystals. Nature Communications, 8:14849 (2017). [LINK]


Mukherjee P, Lim SJ, Wrobel T, Bhargava R, and Smith AM. Measuring and predicting the internal structure of semiconductor nanocrystals through Raman spectroscopy. Journal of the American Chemical Society, 138: 10887-10896 (2016).

Wan Y, Carson JA, Kesler BA, Peng W, Su P, Al-Mulla SA, Lim SJ, Smith AM, Dallesasse JM, and Cunningham BT. Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera. Scientific Reports, 6: 29117 (2016).

Ma L, Liu T-W, Wallig MA, Dobrucki IT, Dobrucki LW, Nelson ER, Swanson KS, and Smith AM. Efficient targeting of adipose tissue macrophages in obesity with polysaccharide nano-carriers. ACS Nano, 10: 6952-6962 (2016).

Lim SJ, Ma L, Schleife A, and Smith AM. Quantum dot surface engineering: toward inert fluorophores with compact size and bright, stable emission. Coordination Chemistry Reviews, 320-321: 216-237 (2016).

Ma L, Tu C, Le P, Chitoor SN, Lim SJ, Zahid MU, Teng KW, Ge P, Selvin PR, and Smith AM. Multidentate polymer coatings for compact and homogeneous quantum dots with efficient bioconjugation. Journal of the American Chemical Society, 138: 3382-3394 (2016).

Lim SJ, McDougle DR, Zahid MU, Das A, and Smith AM. Lipoprotein nanoplatelets: fluorescent, zwitterionic probes with rapid cellular entry. Journal of the American Chemical Society, 138: 64-67 (2016).

Lim SJ, Zahid MU, Le P, Ma L, Entenberg D, Harney AS, Condeelis J, and Smith AM. Brightness-equalized quantum dots. Nature Communications. 6: 8210 (2015).

Grolman JM, Zhang D, Smith AM, Moore JS, and Kilian KA. Rapid extrusion of 3D tumor microenvironments. Advanced Materials, 27: 5512-5517 (2015).

Chung EY, Ochs CJ, Wang Y, Lei L, Qin Q, Smith AM, Strongin AY, Kamm R, Qi Y-X, Lu SY, and Wang YX. Activatable and cell-penetrable multiplex nanosensors for profiling MT1-MMP activity in single cancer cells. Nano Letters, 15: 5025-5032 (2015).

Dobrucki W, Pan D, and Smith AM. Multiscale imaging of nanoparticle drug delivery. Current Drug Targets, 16: 560-570 (2015).

Lane LA, Qian XM, Smith AM, and Nie SM. Physical chemistry of nanomedicine: understanding the complex behaviors of nanoparticles in vivo.  Annual Review of Physical Chemistry, 66: 521-547 (2015).

Wang Y, Cai E, Rosenkranz T, Ge P, Teng K, Lim SJ, Smith AM, Chung HJ, Sachs F, Green WN, Gottlieb P, and Selvin PR. Small quantum dots conjugated to nanobodies as immunofluorescence probes for nanometric microscopy. Bioconjugate Chemistry. 25: 2205-2211 (2014).

Lane LA, Smith AM, and Nie SM*. Compact and blinking-suppressed quantum dots for single-particle tracking in live cells. Journal of Physical Chemistry B. 118: 14140-14147 (2014).

Cai E, Ge P, Lee SH, Jeyifous O, Wang Y, Liu Y, Wilson KM, Lim SJ, Baird MA, Stone JE, Lee KY, Davidson MW, Chung HJ, Schulten K, Smith AM, Green WN, and Selvin PR. Stable small quantum dots for synaptic receptor tracking on live neurons. Angewandte Chemie. 53: 12484-12488 (2014).

Smith AM, Lane LA, and Nie SM.  Mapping the spatial distribution of charge carriers in quantum-confined heterostructures. Nature Communications. 5: 4506 (2014).

Lim SJ, Smith AM, and Nie SM.  The more exotic shapes of semiconductor nanocrystals: emerging applications in bioimaging. Current Opinion in Chemical Engineering. 4: 137-143 (2014).

Ma L, Kohli M and Smith AM. Nanoparticles for combination drug therapy. ACS Nano. 7: 9518-9525 (2013).

Kairdolf BA, Smith AM, Stokes TD, Wang MD, Young AN, and Nie SM. Semiconductor quantum dots for bioimaging and biodiagnostic applications. Annual Review of Analytical Chemistry. 6: 143 (2013).

Smith AM and Nie SM. Compact quantum dots for single-molecule imaging in living cells. Journal of Visualized Experiments. 68: e4236 (2012).